Hyaluronic Acid from Lactococcus lactis


Hyaluronic acid is an important component of articular cartilage, where it is present as a coat around each cell, in the extracellular matrix in tissues. It is used in many medical preparations today.

Most commercially manufactured hyaluronic acid comes from Streptococcus zooepidemicus, a known pathogen. Recently, scientists from the IIT Madras reported overcoming this threat.

Guhan Jayaraman and his team at the Department of Biotechnology, IIT Madras metabolically engineered Lactococcus lactis, the bacterium that ferments milk sugar to lactic acid, to produce hyaluronic acid.

512px-Lactococcus_lactis,_scanning_electron_micrograph Color-enhanced image of Lactococcus lactis – Kenneth Todar, PhD        CC BY 4.0

Can this be used in biological implants?

“Hyaluronic acid from the bacterial fermentation of  L. lactis is bio-compatible”, says Vignesh Muthuvijayan, IIT Madras.

The team chemically cross-linked the hyaluronic acid on hydrolyzed polyethylene terephthalate, commonly known as PET. PET is bio-compatible and does not generate immune reactions. So, it can…

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Letters in Fiction, Malayalam


ഇനിയുമൊത്തിരി ദൂരമിരിപ്പൂ...... മിഴികളിൽ ഒരു തരി മണ്ണ് പറ്റും മുൻപേ “മതിയെടാ, നിന്റെ യാത്ര ഭ്രാന്തു തന്നെ സഹിക്കാൻ പറ്റുന്നില്ല, അപ്പോഴാണ് ഈ തുണ്ടു കവിതകൾ. അഗത്തിയിൽ ഞാൻ നാസിയോട് വിളിച്ചു പറഞ്ഞിട്ടുണ്ട്, നീ കപ്പലിറങ്ങുമ്പോൾ അവൻ  വന്ന് നിന്നെ Pick ചെയ്തുകൊള്ളും. കപ്പലിൽ കയറികഴിയുമ്പോൾ അമ്മയെ വിളിച്ചേക്ക്. അപ്പൊ ഓക്കേ, കാറിൽ നിന്ന് ഇറങ്ങി പോടാ” “ ചേച്ചീ, ഉമ്മാ....” ............................................................................................................................................ലഗൂൺ കപ്പലിലേക്കുള്ള യാത്രക്കാർ എത്രയും പെട്ടന്ന് ബോർഡിങ് പോയിന്റിലേക്കു എത്തേണ്ടതാണ്. സ്കാനിംഗ് സെന്ററിൽ നിന്നുള്ള… Continue reading നിലാമഴ


How India growing in science and technology? A brief note on India Innovation Report.

Image from Clarivate Analytics is a company that owns and operates a collection of subscription-based services focused largely on analytics, including scientific and academic research, patent analytics, regulatory standards, trademark protection, pharmaceutical and biotechnology intelligence, domain brand protection and intellectual property management. Clarivate Analytics, the global leader in providing trusted insights and analytics to… Continue reading How India growing in science and technology? A brief note on India Innovation Report.

D FOR DIVING, ecodives

Hand signals for SCUBA Diving

Conveying what we thought to share, there are several modes of communication medium are been used. Certain are as you by speaking the languages, writing, or even by our tiny expression in our face or by a cute smile. While coming back to Diving, these speaking skills won't applies for obvious reasons. So to overcome… Continue reading Hand signals for SCUBA Diving

Alchemy, chronicles of Sci student, Science topia

Karuvannur River: Responding to tectonics

In most cases we don't find scientific article about our local area and its phenomena, we always  moving around NASA and space. This news article is beautifully written about the research publication on Karuvannur river's past tectonic activity and evolution....... Most river basins in Kerala are very sinuous and have asymmetric basin characteristics. This behaviour… Continue reading Karuvannur River: Responding to tectonics


Reusable Bags

  This image was one of the most discussed one of 2018 and it speaks so many critical issues faced by the earth. This post belongs to the first in the series of Plastic Free July Challenge. You can read the previous post ( in detail) about the Plastic Free July Challenge 2018 here. I… Continue reading Reusable Bags


Plastic Free July Challenge

  Hello folks, It's been nearly 2 months I haven't written anything for you. All of a sudden, today I decided to break my silence. Okay so if you are thinking why I was silent excluding several lame reasons on time/stress management, I was getting ready for a journey. A journey which I was eagerly… Continue reading Plastic Free July Challenge